Search results for "10029 Clinic and Policlinic for Internal Medicine"

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LDL size and subclasses in patients with abdominal aortic aneurysm

2009

Abstract Since the type of dyslipidemia in patients with abdominal aortic aneurysm (AAA) is still insufficiently defined, we measured plasma lipids and analyzed LDL size and subclasses by gradient gel electrophoresis in 30 male patients (69±6 years, BMI: 27±3) with newly diagnosed AAA and in 26 age- and BMI-matched male healthy controls. Patients with AAA had lower HDL-cholesterol ( p p =.0002) and smaller LDL size ( p p =.0210) in relation to controls. Multivariate analysis also showed that small LDL size was independently associated with the presence of AAA ( p =.0350). Increased levels of small, dense LDL may therefore represent a common feature in patients with AAA.

medicine.medical_specialtySmall dense ldl610 Medicine & healthmacromolecular substancesDense LDLSmallLDL sizeGastroenterology2705 Cardiology and Cardiovascular MedicineAortic aneurysmInternal medicinePlasma lipidsmedicineIn patientcardiovascular diseasesbusiness.industrymedicine.diseaseAbdominal aortic aneurysmEndocrinologymedicine.anatomical_structureMale patientcardiovascular systemAbdominal aortic aneurysmAbdomenlipids (amino acids peptides and proteins)10029 Clinic and Policlinic for Internal MedicineaterosclerosiCardiology and Cardiovascular MedicinebusinessDyslipidemia
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Changes of coagulation parameters during high altitude expedition

2010

Data on changes of haemostatic parameters at altitudes above 5000 m are very limited. So far it is unknown, whether altered coagulation could contribute to the development of acute mountain sickness.Thirty four healthy mountaineers were randomised to two acclimatisation protocols and undertook an expedition on Muztagh Ata (7549 m) in China. Tests were performed at five altitudes up to 6865 m. Haemostatic parameters, such as PT, aPTT, D-Dimer, APC-Resistance (APCR), von Willebrand Factor activity (RCo), ADAMTS-13C-Natriuretic Peptide (CNP) were assessed together with Lake Louise AMS score.D-Dimer significantly increased with increasing altitude (median 0.62 to 0.81 mcg/L, p0.0001). During as…

10018 Ophthalmology ClinicAdultMaleChinabusiness.industryAltitude610 Medicine & health2700 General MedicineGeneral MedicineMiddle AgedEffects of high altitude on humansAtmospheric sciencesMountaineeringOphthalmology clinicAltitudeHumansCoagulation (water treatment)MedicineFemalesense organs10029 Clinic and Policlinic for Internal Medicineskin and connective tissue diseasesbusinessBlood CoagulationSwiss Medical Weekly
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Studienendpunkte bei der chronisch-obstruktiven Lungenerkrankung (COPD): „Minimal Clinically Important Difference”

2008

The concept of the minimal clinically important difference (MCID) is intended to provide a measure of relevance for a statistically applied in patients with COPD. Clinically important differences are those differences relevant to the individual patient and important to the patient's life. However, people's difference in a diagnostic parameter perception of what is important vary. Furthermore, physicians may rate the significance of a particular marker and its difference which can be achieved by a pharmacological intervention differently from the patient. Thus, the major problem with defining an MCID for any measure is that the most important differences, which require the most subtle measur…

Pulmonary and Respiratory MedicineCOPDmedicine.medical_specialtyPathologybusiness.industryMinimal clinically important difference610 Medicine & healthmedicine.diseaseTreatment failureTreatment success2740 Pulmonary and Respiratory MedicineIntervention (counseling)medicineIn patientClinical significance10029 Clinic and Policlinic for Internal MedicineIntensive care medicinebusinessPneumologie
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